McNamara R M, Cionni D J
Department of Emergency Medicine, Medical College of Pennsylvania, Philadelphia.
Chest. 1992 Jan;101(1):129-32. doi: 10.1378/chest.101.1.129.
This study examined the utility of a peak expiratory flow rate (PEFR) measurement in the differentiation of acute moderate to severe dyspnea secondary to congestive heart failure or chronic lung disease. A PEFR was determined in 41 episodes of acute respiratory distress in 40 patients prior to emergency department therapy. The mean PEFR +/- SD for the congestive heart failure group (n = 18) was 224 +/- 82 L/min, which was significantly higher (p less than 0.001) than that of the chronic lung disease group (n = 23), which had a mean PEFR of 108 +/- 49 L/min. No single cutoff value allowed 100 percent accurate classification, but the results suggest that the PEFR may be a useful adjunctive tool in the differentiation of acute dyspnea of cardiac vs pulmonary origin.
本研究探讨了呼气峰值流速（PEFR）测量在鉴别因充血性心力衰竭或慢性肺部疾病继发的急性中度至重度呼吸困难中的效用。在40例患者的41次急性呼吸窘迫发作中，于急诊科治疗前测定了PEFR。充血性心力衰竭组（n = 18）的平均PEFR +/-标准差为224 +/- 82升/分钟，显著高于慢性肺部疾病组（n = 23），后者的平均PEFR为108 +/- 49升/分钟（p小于0.001）。没有单一的临界值能实现100%准确分类，但结果表明PEFR可能是鉴别心脏源性与肺源性急性呼吸困难的有用辅助工具。
