白癜风中的二十甲营养不良

Twenty nail dystrophy in vitiligo.

作者信息

Khandpur Sujay, Bansal Arika, Sharma Vinod K, Bhatti Sahibinder Singh, Singh Manoj K

机构信息

Deparment of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

J Dermatol. 2007 Mar;34(3):189-92. doi: 10.1111/j.1346-8138.2007.00247.x.

DOI:10.1111/j.1346-8138.2007.00247.x

PMID:17291300

Abstract

Twenty nail dystrophy (TND) is a manifestation of several dermatoses and its association with vitiligo is rare. It may be consequent upon a common autoimmune insult to the melanocytes and the nail matrix. We report a patient of acrofacial vitiligo who developed TND. Nail matrix biopsy revealed focal lichenoid reaction and chronic inflammatory infiltrate in the dermal papillae and around blood vessels. Hematological, biochemical and serological investigations showed no evidence of other autoimmune diseases.

摘要

二十甲营养不良（TND）是多种皮肤病的一种表现，其与白癜风的关联较为罕见。它可能是黑素细胞和甲母质受到共同自身免疫损伤的结果。我们报告了一名肢端颜面白癜风患者出现了TND。甲母质活检显示局限性苔藓样反应以及真皮乳头和血管周围的慢性炎症浸润。血液学、生化和血清学检查未发现其他自身免疫性疾病的证据。