Mohammadpour M, Jafarinasab M Reza, Javadi M Ali
Ophthalmic Research Center, Labbafi Nejad Medical Center, Tehran, Iran.
Eur J Ophthalmol. 2007 Jan-Feb;17(1):20-8. doi: 10.1177/112067210701700104.
To determine characteristics and final visual and surgical outcomes of patients who experienced early onset postoperative inflammation after cataract surgery and their early and late complications.
This is a prospective case series of 126 patients out of 1500 cases who underwent cataract surgery and experienced early onset postoperative inflammation during the first 2 weeks after cataract surgery. All the patients received complete ocular examinations at onset of signs and symptoms of inflammation. A total of 110 patients with follow-up examinations between 3 and 30 months after recovery of early onset postoperative inflammation (mean follow-up 11.6 months) were enrolled in the next part of the study to evaluate the final visual and surgical outcomes. Background systemic and ocular diseases, type of surgery, type of intraocular lenses and viscoelastic agent, early and late complications, and final best-corrected visual acuity were studied.
Among 1500 patients, 126 cases (8.4%) had early onset postoperative inflammation, 64 cases (50.7%) were male, and 62 cases (49.3%) were female. Early complications were posterior synechia in 9 cases (7.1%), pupillary block in 2 cases (1.5%), and acute rise of intraocular pressure in 6 cases (4.7%). Late complications consisted of posterior capsular opacity in 38 cases (34.5%) and cystoid macular edema in 4 cases (3.2%). Peak of signs and symptoms of inflammation was during 2 weeks after surgery and all patients responded well to topical steroids. Final best-corrected visual acuity (BCVA) was 20/30 and better in 76 cases (69%), between 20/40 and 20/80 in 24 cases (22%), and less than 20/80 in 10 cases (9%). All cases with BCVA less than 20/80 had ocular diseases like choroidal neovascularization scar or age-related macular degeneration, advanced glaucoma, or corneal opacity.
Early onset postoperative inflammation causes pain, decreased vision, and patient anxiety in the acute phase but neither decreases final visual acuity nor has any significant or permanent ocular sequels.
确定白内障手术后早期发生术后炎症的患者的特征、最终视力和手术结果及其早期和晚期并发症。
这是一个前瞻性病例系列研究，从1500例接受白内障手术且在术后前2周内发生早期术后炎症的患者中选取了126例。所有患者在炎症体征和症状出现时均接受了全面的眼部检查。共有110例患者在早期术后炎症恢复后3至30个月接受了随访检查（平均随访11.6个月），纳入研究的下一部分以评估最终视力和手术结果。研究了全身和眼部背景疾病、手术类型、人工晶状体和粘弹剂类型、早期和晚期并发症以及最终最佳矫正视力。
在1500例患者中，126例（8.4%）发生了早期术后炎症，其中男性64例（50.7%），女性62例（49.3%）。早期并发症包括9例（7.1%）的虹膜后粘连、2例（1.5%）的瞳孔阻滞和6例（4.7%）的眼压急性升高。晚期并发症包括38例（34.5%）的后囊膜混浊和4例（3.2%）的黄斑囊样水肿。炎症体征和症状的高峰出现在手术后2周内，所有患者对局部类固醇治疗反应良好。最终最佳矫正视力（BCVA）为20/30及以上的有76例（69%），在20/40至20/80之间的有24例（22%），低于20/80的有10例（9%）。所有BCVA低于20/80的病例均患有眼部疾病，如脉络膜新生血管瘢痕或年龄相关性黄斑变性、晚期青光眼或角膜混浊。
早期术后炎症在急性期会引起疼痛、视力下降和患者焦虑，但既不会降低最终视力，也不会产生任何严重或永久性的眼部后遗症。
