Pulay Tamás, Baki Márta, Bodoky György, Dank Magdolna, Cseh József, Csejtei András, Csömör Sándor, Erfán József, Esik Olga, Faluhelyi Zsolt, Izsó József, Hernádi Zoltán, Kammerer Kinga, Magyar Tamás, Mayer Arpád, Megyery Eva, Moskovits Katalin, Pécsi Lajos, Pikó Béla, Pintér Tamás, Ruzsa Agnes, Szánthó András, Szántó István, Szántó János, Szucs Miklós, Tálos Zsuzsanna, Thurzó László, Kásler Miklós
Orv Hetil. 2006 Dec 31;147(52):2493-500.
Authors presented data of treatment results and course of disease in 487 ovarian cancer patients treated by primary surgery and paclitaxel-carboplatin combination chemotherapy between July 1, 2002 and December 31, 2003.
Most of our patients (87.8%) belonged to the age-group between 40-70 years. Distribution of their histological diagnosis was as 69.6% serous, 10.7% mucinous, 5.1% endometrial and 4.7% undifferentiated carcinoma. The grade distribution was found as 8.4% grade 1, 40.9% grade 2 and 35.9% grade 3.
The primary surgery was evaluated as optimal in 41.7%, suboptimal in 37.3% and exploration was performed in 21.1%. Most patients started chemotherapy 20 days after surgery and 74.2% of them got six courses. During the evaluation period 61 intervallum laparotomies were performed, and resulted on 55.7% optimal debulking. Complete remission was found in 58.9%, and partial remission in 14.7% of patients. This treatment resulted on a complete remission in 40.9% at the follow-up of 12 months.
作者展示了2002年7月1日至2003年12月31日期间487例接受初次手术及紫杉醇 - 卡铂联合化疗的卵巢癌患者的治疗结果和病程数据。
我们的大多数患者（87.8%）年龄在40 - 70岁之间。其组织学诊断分布为浆液性69.6%、黏液性10.7%、子宫内膜样5.1%和未分化癌4.7%。分级分布为1级8.4%、2级40.9%和3级35.9%。
初次手术评估为最佳的占41.7%，次佳的占37.3%，探查手术的占21.1%。大多数患者在术后20天开始化疗，其中74.2%接受了六个疗程。在评估期间进行了61次间隔剖腹手术，55.7%实现了最佳减瘤。58.9%的患者达到完全缓解，14.7%的患者部分缓解。该治疗在12个月随访时40.9%的患者实现了完全缓解。
