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成瘾者对海洛因作用的代偿性和模拟性条件反应。

Compensatory and mimetic conditioned responses to effects of heroin in addicted persons.

作者信息

Trujillo Humberto M, Oviedo-Joekes Eugenia, Vargas Cristina

机构信息

Facultad de Psicología, University of Granada, Spain.

出版信息

Psicothema. 2006 Feb;18(1):59-65.

PMID:17296010
Abstract

Study 1: The aim of this study was to analyze in persons detoxified of heroin, compensatory conditioned responses (CCRs) that are opposite to the unconditioned physiological, and subjective effects that are induced by this substance. The procedure consisted in presenting slides with images of neutral stimuli (NSs) and conditioned stimuli (CSs) of heroin to both non-addicted and detoxified addicted persons. The evaluated responses were heart rate (HR) and desire for heroin (DH). Study 2: The aim was to facilitate the emission of mimetic conditioned responses (MCRs) to the unconditioned physiological, and subjective effects of heroin in detoxified heroin addicts. Three different stimulus series were manipulated: SA, during which the participant remained alone; SB, administration of a needle prick given by the researcher; SC, performance of the "pump" ritual without drug by the participants. The responses measured were HR and DH. The results of both studies are considered, respectively, to be indicators of compensatory and mimetic conditioned responses.

摘要

研究1:本研究的目的是分析已戒除海洛因的人群中与该物质诱发的无条件生理和主观效应相反的代偿性条件反应(CCRs)。研究过程包括向未成瘾者和已戒除成瘾者展示带有中性刺激(NSs)图像的幻灯片以及海洛因的条件刺激(CSs)。所评估的反应为心率(HR)和对海洛因的渴望(DH)。研究2:目的是促使已戒除海洛因成瘾者对海洛因的无条件生理和主观效应产生模仿性条件反应(MCRs)。操控了三个不同的刺激系列:SA,在此期间参与者独自待着;SB,由研究人员进行针刺;SC,参与者进行无药物的“注射”仪式。所测量的反应为心率(HR)和对海洛因的渴望(DH)。两项研究的结果分别被视为代偿性和模仿性条件反应的指标。

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