Sakurai Jun, Hiraki Takao, Mukai Takashi, Mimura Hidefumi, Yasui Kotaro, Gobara Hideo, Hase Soichiro, Fujiwara Hiroyasu, Iguchi Toshihiro, Tajiri Nobuhisa, Aoe Motoi, Sano Yoshifumi, Date Hiroshi, Kanazawa Susumu
Department of Radiology, Okayama University Medical School, Okayama, Japan.
J Vasc Interv Radiol. 2007 Jan;18(1 Pt 1):141-5. doi: 10.1016/j.jvir.2006.10.011.
We describe two cases of intractable pneumothorax that were attributed to a bronchopleural fistula (BPF) after radiofrequency ablation of lung tumors. In both cases, radiofrequency ablation induced necrosis of the lung tissue between the pleural space and the bronchus. The bronchopleural fistula formed after sloughing of the necrotic tissue. Management of the bronchopleural fistula was quite challenging, requiring frequent treatments, including pleurodesis, endobronchial management, and/or surgical repair. In one of the patients, air leakage persisted despite these efforts, and the patient died of acute pneumonia 52 days after the procedure. Although it is rare, with an incidence of 0.6% (2/334) at our institution, intractable pneumothorax due to bronchopleural fistula should be recognized as a risk associated with radiofrequency ablation of lung tumors.
我们描述了两例难治性气胸病例,其病因是肺肿瘤射频消融术后发生支气管胸膜瘘(BPF)。在这两例病例中,射频消融导致胸膜腔与支气管之间的肺组织坏死。坏死组织脱落之后形成了支气管胸膜瘘。支气管胸膜瘘的处理颇具挑战性,需要频繁进行包括胸膜固定术、支气管内处理和/或手术修复在内的治疗。在其中一名患者中,尽管进行了这些治疗,漏气仍持续存在,该患者在术后52天死于急性肺炎。尽管罕见,在我们机构的发生率为0.6%(2/334),但因支气管胸膜瘘导致的难治性气胸应被视为与肺肿瘤射频消融相关的一种风险。