Jones O M, John S K P, Horseman N, Lawrance R J, Fozard J B J
Department of Colorectal Surgery, Royal Bournemouth Hospital, Bournemouth, UK.
Colorectal Dis. 2007 Mar;9(3):253-7. doi: 10.1111/j.1463-1318.2006.01131.x.
Few studies on colorectal cancer look at the one-third of patients for whom treatment fails and who need a management strategy for death. This paper has examined the mode and place of death in patients with colorectal cancer.
This study was a review of 209 deaths, analysed between January 2001 and September 2004 by retrospective review of a prospectively collected database.
A total of 118 patients (group 1) had undergone resection of their primary colorectal cancer, 20 (group 2) had had a defunctioning stoma or bypass surgery and the remaining 71 patients (group 3) had either had no surgery, an open and close laparotomy or had a colonic stent. One hundred and fifty-six (75%) patients died of colorectal cancer with the remainder dying of other causes. The number of admissions to hospital and the number of days spent in hospital from diagnosis to death were greatest in group 1. Overall, only 34 patients (22%) dying from colorectal cancer died at home. Forty (26%) died in hospital and 70 (45%) died in a palliative care unit.
Patients dying from colorectal cancer who undergo surgical resection of their primary tumour spend more time between diagnosis and death in hospital. They are also more likely to die in hospital than patients treated by surgical palliation or nonsurgically. Patients who are treated palliatively from the outset (group 3) are most likely to die at home. If hospital is accepted as an appropriate place for death from colorectal cancer, then greater provision for this should be made.
关于结直肠癌的研究中,很少有针对三分之一治疗失败且需要死亡管理策略的患者展开。本文研究了结直肠癌患者的死亡方式和地点。
本研究回顾了209例死亡病例,通过对前瞻性收集的数据库进行回顾性分析,分析时间为2001年1月至2004年9月。
共有118例患者(第1组)接受了原发性结直肠癌切除术,20例(第2组)进行了造口减压术或旁路手术,其余71例患者(第3组)未接受手术、进行了剖腹探查术或置入了结肠支架。156例(75%)患者死于结直肠癌,其余死于其他原因。从诊断到死亡,第1组患者的住院次数和住院天数最多。总体而言,仅34例(22%)死于结直肠癌的患者在家中死亡。40例(26%)在医院死亡,70例(45%)在姑息治疗病房死亡。
接受原发性肿瘤手术切除的结直肠癌死亡患者,从诊断到死亡期间在医院花费的时间更多。与接受手术姑息治疗或非手术治疗的患者相比,他们在医院死亡的可能性也更大。从一开始就接受姑息治疗的患者(第3组)最有可能在家中死亡。如果医院被认为是结直肠癌患者死亡的合适场所,那么应为此提供更多条件。