Nikishova E I, Nizovtseva N I, Mar'iandyshev A O
Probl Tuberk Bolezn Legk. 2006(12):54-7.
Analysis of tuberculosis mortality in the civil sector of the Arkhangelsk Region in 2004 revealed that 55.4% of all death cases had been notified in patients with tuberculosis caused by multidrug-resistant Mycobacterium tuberculosis (MBT). In the above group of patients, 101 (85.6%) patients had not received chemotherapy with drug MBT resistance being kept in mind: tuberculosis autopsy was established in 15 patients with multidrug-resistance MBT at autopsy; in 5 patients MBT resistance to 7 and 8 antituberculosis agents had ruled out the use of etiotropic therapy; 81 patients had not received adequate treatment due to the shortage and spectrum of second-line antituberculosis drugs. The second cause of death from tuberculosis was the acutely progressive, disseminated forms of the disease, even, during treatment, leading to a fatal outcome, which were detectable in patients with a new case of tuberculosis (33.8% of all deaths) and its recurrence (5.6%).
对阿尔汉格尔斯克州2004年民用部门结核病死亡率的分析显示，在所有死亡病例中，55.4%的病例是由耐多药结核分枝杆菌（MBT）引起的结核病患者。在上述患者组中，101例（85.6%）患者未接受考虑到MBT耐药性的化疗：尸检时在15例耐多药MBT患者中确定为结核性尸检；5例患者因MBT对7种和8种抗结核药物耐药而无法进行特效治疗；81例患者因二线抗结核药物短缺和种类有限而未接受充分治疗。结核病死亡的第二个原因是疾病的急性进展性、播散性形式，即使在治疗期间也会导致致命后果，在新诊断的结核病患者（占所有死亡病例的33.8%）及其复发患者（5.6%）中均可检测到。
