Letendre E D, Miron P, Roberts K D, Langlais J
University of Montreal, Maisonneuve-Rosemont Hospital Research Center, Quebec, Canada.
Fertil Steril. 1992 Jan;57(1):193-8.
To search for the presence of platelet-activating factor (PAF) acetylhydrolase activity in human seminal plasma.
Experimental.
Reproductive laboratory in a university-affiliated hospital research center.
Human male volunteers were selected on the basis of apparent normal health.
Human seminal plasma contained significant levels of PAF-acetylhydrolase activity. Enzymatic hydrolysis of PAF displayed typical kinetics and was a calcium-independent process. Platelet-activating factor acetylhydrolase in seminal plasma was associated with a very high-density lipoprotein fraction. Enzymatic activity was independent of sperm count and motility.
Human seminal plasma contains significant levels of PAF acetylhydrolase. This enzyme may be an important factor in the regulation of PAF concentration and activity.
探寻人类精浆中血小板活化因子（PAF）乙酰水解酶活性的存在情况。
实验性研究。
大学附属医院研究中心的生殖实验室。
根据明显的健康状况选择人类男性志愿者。
人类精浆含有显著水平的PAF-乙酰水解酶活性。PAF的酶促水解呈现典型动力学，且是一个不依赖钙的过程。精浆中的血小板活化因子乙酰水解酶与极高密度脂蛋白部分相关。酶活性与精子计数和活力无关。
人类精浆含有显著水平的PAF乙酰水解酶。这种酶可能是调节PAF浓度和活性的一个重要因素。
