Alyasin Soheila, Amin Reza
Department of Clinical Immunology and Allergy, Clinical Immunology and Allergy Research Laboratory, Shiraz University of Medical Sciences, Shiraz, Iran.
Iran J Allergy Asthma Immunol. 2007 Mar;6(1):27-31.
Allergic rhinitis is the most common cause of allergic diseases. The recent guidelines of Allergic Rhinitis and its Impact on Asthma (ARIA) group, classified it to intermittent (less than 4 days per week and for less than 4 weeks) and persistent (more than 4 days per week or lasting more than 4 weeks regardless of the number of days per week). The present study evaluates the patients with ARIA classification. The patients referred to Motahhari Clinic (Shiraz, Iran) were evaluated. Age, sex, seasonal or perennial, intermittent or persistent type, duration, sneezer or blocker, diurnal change and presence of allergic conjunctivitis were recorded. The patients who had one or more symptoms of; impairment of sleep, daily activity or work in school or troublesome symptoms had moderate to severe disease and those who did not have these problems have mild disease. The information of 96 patients (46 male and 50 female) were analysed (mean age+/-SD: 24.45+/-10.37 years). The mean duration of disease was 4.26+/-4.12 years, was more in female (P<0.05). Seasonal allergic rhinitis was present in 49 (52%) patients; 30 male, 19 female (P=0.007), perennial in 15 (16%), 1 male, 14 female and mixed type in 29 (30%); 11 male, 18 female. Mild intermittent rhinitis was diagnosed in only 2 (2%) patients, 1 male and 1 female, mild persistent rhinitis in 23 (24%); male 11, female 12; moderate/severe intermittent rhinitis in 4 (4%); 3 male, 1 female; and moderate/severe persistent rhinitis in 56 (58%); 22 male, 34 female (P<0.05). Fifty-seven percent were more sneezer and 36% were more blocker type, sneezers suffered more in days and others more at nights. Others were both sneezer and blocker. Sixty percent had allergic conjunctivitis too, 76% of them were moderate/severe persistent, and 85% were in seasonal or mixed groups. Eleven patients (12%), in persistent group, had history of asthma. Family history of allergic rhinitis and asthma was found in 53% and in 25% of patients, respectively. According to new guidelines for classification of allergic rhinitis, most of the patients are moderate to severe types. The classification of allergic rhinitis to seasonal and perennial disease is not proportional to intermittent and persistent types of classification. .
变应性鼻炎是过敏性疾病最常见的病因。变应性鼻炎及其对哮喘的影响(ARIA)小组的最新指南将其分为间歇性(每周少于4天且持续少于4周)和持续性(每周超过4天或持续超过4周,无论每周天数)。本研究对ARIA分类的患者进行评估。对转诊至莫塔哈里诊所(伊朗设拉子)的患者进行评估。记录年龄、性别、季节性或常年性、间歇性或持续性类型、病程、喷嚏型或鼻塞型、昼夜变化以及变应性结膜炎的存在情况。有一项或多项症状(睡眠障碍、日常活动或学校学习或工作受影响或有困扰症状)的患者患有中重度疾病,而没有这些问题的患者患有轻度疾病。分析了96例患者(46例男性和50例女性)的信息(平均年龄±标准差:24.45±10.37岁)。疾病的平均病程为4.26±4.12年,女性更长(P<0.05)。49例(52%)患者为季节性变应性鼻炎,男性30例,女性19例(P=0.007);15例(16%)为常年性,男性1例,女性14例;29例(30%)为混合型,男性11例,女性18例。仅2例(2%)患者被诊断为轻度间歇性鼻炎,男性1例,女性1例;23例(24%)为轻度持续性鼻炎,男性11例,女性12例;4例(4%)为中重度间歇性鼻炎,男性3例,女性1例;56例(58%)为中重度持续性鼻炎,男性22例,女性34例(P<0.05)。57%的患者喷嚏较多,36%的患者鼻塞较多,喷嚏型患者白天症状更严重,鼻塞型患者夜间症状更严重。其他患者既有喷嚏又有鼻塞。60%的患者也有变应性结膜炎,其中76%为中重度持续性,85%属于季节性或混合型。持续性组中有11例患者(12%)有哮喘病史。分别有53%和25%的患者有变应性鼻炎和哮喘家族史。根据变应性鼻炎的新分类指南,大多数患者为中重度类型。变应性鼻炎分为季节性和常年性疾病与间歇性和持续性分类类型不成比例。