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与阿扎那韦治疗相关的QT间期延长和尖端扭转型室速。

Prolonged QT interval and torsades de pointes associated with atazanavir therapy.

作者信息

Ly Tam, Ruiz Maria Elena

机构信息

Department of Medicine, Washington Hospital Center, Washington, DC, USA.

出版信息

Clin Infect Dis. 2007 Mar 15;44(6):e67-8. doi: 10.1086/511875. Epub 2007 Feb 1.

DOI:10.1086/511875
PMID:17304444
Abstract

We report, to our knowledge, the first documented case of torsades de pointes associated with atazanavir therapy. This case serves to highlight the need to monitor patients receiving atazanavir therapy who have risk factors for QT interval prolongation, such as female sex, bradycardia, electrolyte abnormalities, congestive heart failure, and a baseline prolonged QT interval.

摘要

据我们所知，我们报告了首例有文献记载的与阿扎那韦治疗相关的尖端扭转型室速病例。该病例凸显了对接受阿扎那韦治疗且有QT间期延长风险因素的患者进行监测的必要性，这些风险因素包括女性、心动过缓、电解质异常、充血性心力衰竭以及基线QT间期延长。

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