Liu Tong, Li Guangping
Int J Cardiol. 2008 Jan 11;123(2):193-4. doi: 10.1016/j.ijcard.2006.11.135. Epub 2007 Feb 15.
The interplay between left atrial (LA) dilatation and atrial fibrillation (AF) has been well established, but the underlying mechanisms of this vicious circle are not fully understood. Recent studies indicated that pulmonary vein (PV) dilatation is implicated in the development of AF. On the other hand, PV dilatation has been associated with LA dilatation. It is therefore reasonable to assume that PV dilatation represents a common pathophysiologic pathway between LA enlargement and AF.
左心房(LA)扩张与心房颤动(AF)之间的相互作用已得到充分证实,但其恶性循环的潜在机制尚未完全明确。近期研究表明,肺静脉(PV)扩张与AF的发生有关。另一方面,PV扩张与LA扩张相关。因此,合理的假设是PV扩张代表了LA扩大与AF之间的共同病理生理途径。