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1996 - 2004年美国儿童、青少年及成人住院患者中双相情感障碍诊断率上升。

Increased rates of bipolar disorder diagnoses among U.S. child, adolescent, and adult inpatients, 1996-2004.

作者信息

Blader Joseph C, Carlson Gabrielle A

机构信息

Department of Psychiatry and Behavioral Science, Stony Brook State University of New York, Stony Brook, New York 11794-8790, USA.

出版信息

Biol Psychiatry. 2007 Jul 15;62(2):107-14. doi: 10.1016/j.biopsych.2006.11.006. Epub 2007 Feb 16.

DOI:10.1016/j.biopsych.2006.11.006
PMID:17306773
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2001259/
Abstract

BACKGROUND

Volatile, aggressive behavior is the chief complaint that brings children to inpatient psychiatric care. These difficulties are increasingly conceptualized as bipolar disorder (BD). The impact of doing so on clinical diagnoses in clinical care is uncertain.

METHODS

We extracted records from the annual National Hospital Discharge Survey (NHDS) for which a psychiatric diagnosis was primary and examined trends in the rates of hospitalization for BD.

RESULTS

Population-adjusted rates of hospital discharges of children with a primary diagnosis of BD increased linearly over survey years. The rate in 1996 was 1.3 per 10,000 U.S. children and climbed to 7.3 per 10,000 U.S. children in 2004. Bipolar disorder related discharges also increased fourfold among adolescents. Adults showed a more modest, though still marked, rise of 56%. Bipolar disorder related hospitalization was more prevalent among female adolescents and adults, while male children had larger risk than female children. Children's BD diagnoses tended not to specify a prevailing mood state, while depression and psychotic features were the most common codes for adults. Black individuals, especially men, had lower rates of BD diagnoses in early survey years, but more recently their rate of BD related hospitalizations has exceeded other NHDS race groups.

CONCLUSIONS

Higher rates of inpatient admissions among youth associated with BD may reflect greater appreciation of the importance of affective dysregulation in this patient group or "upcoding" to putatively more severe conditions for reimbursement or administrative reasons. Further study is warranted to examine this shift's causes and implications for treatments and outcomes.

摘要

背景

反复无常、攻击性的行为是导致儿童接受住院精神科治疗的主要原因。这些问题越来越多地被归类为双相情感障碍(BD)。这样做对临床护理中临床诊断的影响尚不确定。

方法

我们从年度全国医院出院调查(NHDS)中提取了以精神科诊断为主的记录,并检查了双相情感障碍住院率的趋势。

结果

以双相情感障碍为主要诊断的儿童的人口调整出院率在调查年份中呈线性上升。1996年的发病率为每10000名美国儿童中有1.3例,到2004年攀升至每10000名美国儿童中有7.3例。双相情感障碍相关的出院人数在青少年中也增加了四倍。成年人的增幅较为温和,但仍很显著,为56%。双相情感障碍相关住院在女性青少年和成年人中更为普遍,而男性儿童的风险高于女性儿童。儿童双相情感障碍的诊断往往未明确占主导的情绪状态,而抑郁和精神病特征是成年人最常见的诊断编码。在早期调查年份,黑人个体,尤其是男性,双相情感障碍的诊断率较低,但最近他们双相情感障碍相关的住院率超过了其他NHDS种族群体。

结论

与双相情感障碍相关的青少年住院率较高,可能反映出对这一患者群体情感失调重要性的更高认识,或者是出于报销或行政原因而“升级编码”到假定更严重的疾病。有必要进一步研究以检查这种转变的原因及其对治疗和结果的影响。

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