Hartman H A, Robison R L, Visscher G E
Vet Pathol. 1975;12(3):210-9. doi: 10.1177/030098587501200306.
Bodies similar to acidophilic intracytoplasmic inclusions were found by light microscopy in the pancreatic acinar cells of 56 of 174 (32%) healthy male and female purebred Beagles and 14 of 97 (14%) of healthy male mongrel dogs. The inclusions were ovoid, acidophilic and often granular with basophilic particulates. Many seemed to be enclosed within halos of various widths. Electron microscopically the inclusions consisted of whorls of rough endoplasmic reticulum, vacuoles, and cytoplasmic organelles in various stages of decomposition. These inclusion bodies were interpreted as evidence of focal intracytoplasmic degradation. They appeared similar to the dense ribosomal autophagic vacuoles, hitherto described only in association with various experimental procedures.
在174只健康的雄性和雌性纯种比格犬中的56只（32%）以及97只健康雄性杂种犬中的14只（14%）的胰腺腺泡细胞中，通过光学显微镜发现了类似于嗜酸性胞质内包涵体的物体。这些包涵体呈卵圆形，嗜酸性，且通常带有嗜碱性颗粒。许多包涵体似乎被不同宽度的晕圈所包围。电子显微镜下，这些包涵体由处于不同分解阶段的粗面内质网、液泡和细胞质细胞器的漩涡组成。这些包涵体被解释为局灶性胞质降解的证据。它们看起来类似于致密核糖体自噬泡，迄今为止仅在各种实验过程中被描述过。
