Hartman J M, Kelder H C, Ackerstaff R G A, Swieten H A, Vermeulen F E E, Bogers A J J C
Department of Cardiothoracic Surgery, Thoraxcentre, Erasmus Medical Centre, Rotterdam, The Netherlands.
J Cardiovasc Surg (Torino). 2007 Feb;48(1):59-66.
To correlate supraclavicular ultrasonography with angiographically patent and string sign left internal mammary artery (LIMA) to left anterior descending artery (LAD) grafts.
Sixteen patients with a single LIMA anastomosis to the LAD were prospectively entered in a follow-up study. The supraclavicular ultrasonography of the LIMA origin was studied preoperatively and at 5.3+/-3.6 months and 1.7+/-0.4 year postoperatively. At the late postoperative ultrasonography electrocardiographically controlled hyperemic response was also studied for 6 min. Control angiography was performed at 1.5+/-0.8 year. Differences within groups were tested with a paired t-test and between groups with an unpaired t-test.
Control angiography showed in 13 patients (group I) a patent LIMA graft and in 3 patients (group II) a string sign LIMA graft. Preoperative blood velocities were not significantly different between groups. Postoperatively, both groups revealed higher diastolic and lower systolic blood velocities compared to preoperative values. The blood velocities at rest did not change in group I and all velocities decreased in group II in time postoperatively. The blood velocities in maximal hyperemic response increased significantly within the groups and were not significantly different between the groups. No ischemia could be detected electrocardiographically during hyperemic response and no patient presented angina.
Both groups showed a shift towards coronary type diastolic blood velocities at rest and at hyperaemic response. Significant hyperemic response was also present in string sign LIMA grafts and demonstrates response capacity to increased myocardial oxygen demand.
将锁骨上超声检查与血管造影显示通畅及呈线样征的左乳内动脉(LIMA)至左前降支动脉(LAD)搭桥血管进行相关性研究。
16例接受LIMA至LAD单支搭桥手术的患者前瞻性纳入一项随访研究。术前及术后5.3±3.6个月和1.7±0.4年对LIMA起始处进行锁骨上超声检查。术后晚期超声检查时,还对心电图控制的充血反应进行6分钟研究。在1.5±0.8年时进行对照血管造影。组内差异采用配对t检验,组间差异采用非配对t检验。
对照血管造影显示,13例患者(I组)LIMA搭桥血管通畅,3例患者(II组)LIMA搭桥血管呈线样征。术前两组间血流速度无显著差异。术后,两组舒张期血流速度均高于术前,收缩期血流速度均低于术前。I组静息时血流速度无变化,II组所有血流速度术后均随时间下降。两组最大充血反应时的血流速度均显著增加,且组间无显著差异。充血反应期间心电图未检测到缺血,无患者出现心绞痛。
两组在静息和充血反应时均呈现向冠状动脉型舒张期血流速度转变。呈线样征的LIMA搭桥血管也存在显著的充血反应,表明其对增加的心肌氧需求有反应能力。