Knight Karen H, Brand Frances M, Mchaourab Ali S, Veneziano Giorgio
Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio 44108, USA.
Croat Med J. 2007 Feb;48(1):22-34.
Management of chronic pain by intrathecal delivery is gaining increasing use. The aim of this article is to review the literature pertinent to implantable devices used for treatment of chronic pain, and to highlight what is known. Articles were obtained from Medline database and reviewed. Practical patient selection criteria, trial management, and surgical technique are described. Expert consensus guidelines for intrathecal medication use are also reviewed. Finally, an exhaustive description of known complications and future implications is discussed. We concluded that intrathecal pump seems to be overused, while there is still weak evidence to support its outcome. It is also recommended that future research focus on the outcome, measured by functional parameters rather than commonly used pain scores.
鞘内给药治疗慢性疼痛的应用越来越广泛。本文旨在回顾与用于治疗慢性疼痛的植入式装置相关的文献,并突出已了解的情况。文章从Medline数据库获取并进行了综述。描述了实际的患者选择标准、试验管理和手术技术。还综述了鞘内用药的专家共识指南。最后,讨论了已知并发症和未来影响的详尽描述。我们得出结论,鞘内泵似乎使用过度,而支持其疗效的证据仍然不足。还建议未来的研究应聚焦于以功能参数而非常用的疼痛评分来衡量的疗效。