Sieunarine K, Shapiro S, Al Obaidi M J, Girling J
Department of Obstetrics and Gynaecology, West Middlesex University Hospital, Middlesex, UK.
BJOG. 2007 Apr;114(4):505-7. doi: 10.1111/j.1471-0528.2007.01234.x. Epub 2007 Feb 19.
A 35-week pregnant 38-year-old woman presented with isolated thrombocytopenia (platelet count 4 x 10(9)/l). Investigations confirmed immune thrombocytopenic purpura, and she received treatment with prednisolone and intravenous immunoglobulins with no increment in the platelet count. At 37 and 38 weeks of the pregnancy, she received two doses of WinRho (anti-D immunoglobulin) at 50 microg/kg. Five days later, with a platelet count of 46 x 10(9)/l, she had an uncomplicated normal vaginal delivery. WinRho is a useful adjunct to other first-line treatment modalities for immune thrombocytopenia in pregnancy.
一名38岁、怀孕35周的女性出现单纯性血小板减少（血小板计数4×10⁹/L）。检查确诊为免疫性血小板减少性紫癜，她接受了泼尼松龙和静脉注射免疫球蛋白治疗，但血小板计数未增加。在妊娠37周和38周时，她接受了两剂50μg/kg的WinRho（抗D免疫球蛋白）。五天后，血小板计数为46×10⁹/L时，她顺利进行了正常阴道分娩。WinRho是妊娠期免疫性血小板减少症其他一线治疗方式的有用辅助药物。
