Adderley R J, Rogers P C, Shaw D, Wadsworth L D
Can Med Assoc J. 1984 Apr 1;130(7):894-6.
A 15-year-old girl with a 9-year history of idiopathic thrombocytopenic purpura resistant to high-dose steroid therapy and to splenectomy was admitted to hospital at 35 weeks' gestation with a platelet count of 10 X 10(9)/L. The bleeding time was normal, and measures of platelet aggregation were nearly so. Treatment with high intravenous doses of polyvalent immune globulin led to a rise in the platelet count to more than 110 X 10(9)/L within 5 days. An elective cesarean section was performed through the lower uterine segment with good hemostasis. After delivery the platelet count fell to its former level, but no postpartum bleeding occurred. There was a brief episode of thrombocytopenia in the infant, with some petechiae but no other hemorrhagic manifestations. No untoward effects of the immune globulin infusion were observed in either mother or daughter.
一名15岁女孩，患特发性血小板减少性紫癜9年，对大剂量类固醇治疗和脾切除术均耐药。孕35周时因血小板计数为10×10⁹/L入院。出血时间正常，血小板聚集检测结果也接近正常。静脉注射大剂量多价免疫球蛋白治疗后，5天内血小板计数升至110×10⁹/L以上。经子宫下段行择期剖宫产，止血良好。产后血小板计数降至先前水平，但未发生产后出血。婴儿有短暂的血小板减少发作，出现一些瘀点，但无其他出血表现。母亲和女儿均未观察到免疫球蛋白输注的不良影响。
