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与慢性背痛共病的临床失眠的患病率及其相关因素

Prevalence and correlates of clinical insomnia co-occurring with chronic back pain.

作者信息

Tang Nicole K Y, Wright Kelly J, Salkovskis Paul M

机构信息

Department of Psychology, Institute of Psychiatry, King's College London, London, UK.

出版信息

J Sleep Res. 2007 Mar;16(1):85-95. doi: 10.1111/j.1365-2869.2007.00571.x.

Abstract

Given the suggestion of a reciprocal relationship between sleep and pain and the recognition of sleep as an important parameter in determining quality of life, there is increasing research interest in sleep disturbance linked to chronic pain. The present study aimed to provide an estimate of the prevalence of 'clinical insomnia' in patients attending a specialist pain clinic and identify factors associated with it. Seventy chronic back pain patients and 70 gender- and age-matched pain-free controls completed a set of questionnaires measuring sleep (Insomnia Severity Index; ISI), pain (Short-Form McGill Pain Questionnaire) and a selection of general and specific psychological variables (Hospital Anxiety and Depression Scale, Short Health Anxiety Inventory). Scores suggestive of clinical insomnia (ISI > or = 15) were noted in 53% of chronic pain patients, when compared with only 3% in pain-free controls. Significant positive correlations with insomnia severity were detected for all six variables of interest (pain intensity, sensory pain ratings, affective pain ratings, general anxiety, general depression and health anxiety). Affective pain ratings and health anxiety were the best predictors of insomnia severity in this sample, accounting for 30% of the total variance, even when present pain intensity was controlled for. Affective pain remained as a significant predictor of insomnia severity when both the effect of pain intensity and the effects of anxiety and depression were controlled for. Future research should consider investigating the role of pain appraisal and health anxiety in the development and manifestation of insomnia concomitant to chronic pain.

摘要

鉴于睡眠与疼痛之间存在相互关系的提示,以及认识到睡眠是决定生活质量的重要参数,与慢性疼痛相关的睡眠障碍越来越受到研究关注。本研究旨在估计专科疼痛诊所患者中“临床失眠”的患病率,并确定与之相关的因素。70名慢性背痛患者和70名年龄及性别匹配的无疼痛对照者完成了一组问卷,这些问卷用于测量睡眠(失眠严重程度指数;ISI)、疼痛(简短麦吉尔疼痛问卷)以及一系列一般和特定的心理变量(医院焦虑抑郁量表、简短健康焦虑量表)。53%的慢性疼痛患者存在提示临床失眠的评分(ISI≥15),而无疼痛对照者中这一比例仅为3%。在所关注的所有六个变量(疼痛强度、感觉性疼痛评分、情感性疼痛评分、一般焦虑、一般抑郁和健康焦虑)中,均检测到与失眠严重程度存在显著正相关。在本样本中,情感性疼痛评分和健康焦虑是失眠严重程度的最佳预测因素,即使在控制了当前疼痛强度的情况下,它们仍占总方差的30%。当同时控制疼痛强度以及焦虑和抑郁的影响时,情感性疼痛仍然是失眠严重程度的显著预测因素。未来的研究应考虑调查疼痛评估和健康焦虑在慢性疼痛伴发失眠的发生和表现中的作用。

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