El Khaldi M, Pernter P, Ferro F, Alfieri A, Decaminada N, Naibo L, Bonatti G
Servizio di Radiologia, Azienda Sanitaria di Bolzano, Via L. Bohler 5, I-39100 Bolzano, Italy.
Radiol Med. 2007 Feb;112(1):123-37. doi: 10.1007/s11547-007-0126-8. Epub 2007 Feb 22.
The leading cause of a nontraumatic subarachnoid haemorrhage is rupture of an intracranial aneurysm. The aim of this study was to assess the usefulness of multislice computed tomography angiography (CTA) in identifying and evaluating cerebral aneurysms by comparing it with intra-arterial digital subtraction angiography (DSA) and intraoperative findings.
During a 20-month period (June 2004 and February 2006), 130 patients with a CT diagnosis of nontraumatic acute subarachnoid haemorrhage were prospectively recruited to this study and underwent 16-detector CTA and DSA (57 men, 73 women; mean age 59.5 years). Twenty-five patients who underwent DSA alone postclipping were excluded. CTA and DSA were evaluated by the performing radiologist to assess the presence of one or more aneurysms and their morphological characteristics.
CTA detected 133 aneurysms, whereas DSA identified 134: the aneurysm missed by CTA was 2 mm in size.
CTA is fast and relatively noninvasive, and its sensitivity appears similar to that of DSA in detecting and evaluating intracranial aneurysms, even those smaller than 3 mm. This study confirms the value of CTA as the primary imaging technique in subarachnoid haemorrhage, with DSA reserved for selected patients.
非创伤性蛛网膜下腔出血的主要原因是颅内动脉瘤破裂。本研究的目的是通过将多层计算机断层血管造影(CTA)与动脉数字减影血管造影(DSA)及术中发现进行比较,评估其在识别和评估脑动脉瘤方面的效用。
在20个月期间(2004年6月至2006年2月),前瞻性招募了130例CT诊断为非创伤性急性蛛网膜下腔出血的患者,这些患者均接受了16排CTA和DSA检查(男性57例,女性73例;平均年龄59.5岁)。排除了25例仅在夹闭术后接受DSA检查的患者。由执行检查的放射科医生对CTA和DSA进行评估,以评估是否存在一个或多个动脉瘤及其形态特征。
CTA检测到133个动脉瘤,而DSA识别出134个:CTA漏诊的动脉瘤大小为2毫米。
CTA快速且相对无创,在检测和评估颅内动脉瘤方面,其敏感性似乎与DSA相似,即使是小于3毫米的动脉瘤。本研究证实了CTA作为蛛网膜下腔出血主要成像技术的价值,DSA则保留用于特定患者。