Kruglikov R I, Aleksandrovskaia M M, Dish T N
Zh Vyssh Nerv Deiat Im I P Pavlova. 1975 May-Jun;25(3):471-6.
Reproduction of defensive conditioned reflexes elaborated before a 96-hour deprivation of paradoxal sleep (DPS) in rats was sharply disturbed immediately after DPS, but became normal 24 hours later. Elaboration of conditioned reflexes immediately after DPS is followed by a disturbance of their reproduction, while such elaboration 24 hours after DPS does not affect their subsequent reproduction. It is assumed that dissociated learning plays an important part in the origin of the disclosed disturbances of conditioned activity. Morphological investigation of the animals' brain immediately after DPS revealed activation of neuroglia with productive-dystrophic changes of astrocytes, an increase in the sizes of nuclei of neurones in the motor cortex and hippocampus, and pronounced vascular changes. A day after DPS the changes of the astrocyte glia and the vessels are less pronounced, and the sizes of neurone nuclei in the motor cortex diminish.
大鼠在96小时快速眼动睡眠剥夺（DPS）之前建立的防御性条件反射，在DPS后立即进行重现时受到严重干扰，但在24小时后恢复正常。在DPS后立即建立条件反射，随后其重现会受到干扰，而在DPS后24小时建立条件反射则不会影响其随后的重现。据推测，分离学习在已揭示的条件活动障碍的起源中起重要作用。在DPS后立即对动物大脑进行形态学研究，结果显示神经胶质细胞被激活，星形胶质细胞出现增生性营养不良变化，运动皮层和海马体中神经元细胞核大小增加，并且血管发生明显变化。在DPS一天后，星形胶质细胞和血管的变化不太明显，运动皮层中神经元细胞核的大小减小。
