Göritz Stefan, Schelkle Helmut, Rein Joachim-Gerd, Urbanek Simon
Department of Thoracic and Cardiovascular Surgery, SANA Hospital, Stuttgart, Germany.
Perfusion. 2006 Nov;21(6):367-71. doi: 10.1177/0267659106070564.
The arterial filter (AF) and the dynamic bubble trap (DBT) reduce the number of air microbubbles passing through these devices. The aim of the study was to confirm that the DBT diminishes microbubbles in the arterial line similar to, or better than, the AF, and can replace it.
In a clinical study, we evaluated 60 patients undergoing cardiopulmonary bypass surgery, divided into two groups (30 patients each). In the first group, we used an open extracorporeal system, and in the second group, a closed system. For 15 patients in each group, the AF was incorporated, the other 15 patients received the DBT. The microbubbles were counted before and after the AF or DBT, using two-channel-ultrasonic Doppler devices.
The exposure of patients to small bubbles (< 45 microm) is significantly higher in the AF than in the DBT group. The DBT reduces large bubbles (> 45 microm) better than the AF, with a rate exceeding 16%.
The use of the DBT instead of the AF yields higher air microbubble removal efficacy, allowing replacement of the AF, assuming the AF is used for air removal purpose only.
动脉滤器(AF)和动态气泡捕捉器(DBT)可减少通过这些装置的空气微泡数量。本研究的目的是证实DBT在动脉管路中减少微泡的效果与AF相似或优于AF,并可替代AF。
在一项临床研究中,我们评估了60例行体外循环手术的患者,分为两组(每组30例)。第一组使用开放体外循环系统,第二组使用封闭系统。每组15例患者使用AF,另外15例患者使用DBT。使用双通道超声多普勒装置在AF或DBT前后对微泡进行计数。
患者接触小气泡(<45微米)的情况在AF组显著高于DBT组。DBT减少大气泡(>45微米)的效果优于AF,减少率超过16%。
使用DBT而非AF可产生更高的空气微泡清除效果,在仅将AF用于空气清除目的的情况下,可替代AF。