Perthel Mathias, Kseibi Samer, Bendisch Andreas, Laas Joachim
Division of Cardiac Surgery, Herz-Kreislauf-Klinik, Bad Bevensen, Germany.
Perfusion. 2003 Sep;18(5):325-9. doi: 10.1191/0267659103pf678oa.
Microemboli during extracorporeal circulation (ECC) might be a reason for postoperative neuropsychological dysfunction. This case report shows that reduction of microbubbles in the arterial line, as well as high intensity transient signals (HITS) in the middle cerebral artery (MCA), could be accomplished by use of a dynamic bubble trap (DBT) during routine coronary artery bypass graft (CABG) surgery in a 63-year-old male. The DBT was placed after the arterial filter, an ultrasound Doppler device was used for detection of microemboli before and after the DBT. HITS were measured by a transcranial ultrasound Doppler in both MCAs. For first 32 min of ECC, the DBTwas excluded; 54 916 microbubbles and 507 HITS were counted. In the next 30 min, blood flow was directed through the DBT. This led to a significant reduction of microbubbles from 55 888 to 18 237; accordingly, only 120 HITS were registered. A DBT, integrated in ECC for routine CABG, effectively reduces air bubbles, thus protecting the cerebrovascular system from microembolization, as demonstrated by lower HITS counts.
体外循环(ECC)期间的微栓子可能是术后神经心理功能障碍的一个原因。本病例报告显示,在一名63岁男性的常规冠状动脉旁路移植术(CABG)中,使用动态气泡捕捉器(DBT)可减少动脉管路中的微泡以及大脑中动脉(MCA)中的高强度瞬态信号(HITS)。DBT放置在动脉滤器之后,使用超声多普勒装置在DBT前后检测微栓子。通过经颅超声多普勒在双侧MCA中测量HITS。在ECC的前32分钟,排除DBT;计数到54916个微泡和507个HITS。在接下来的30分钟内,血流通过DBT。这导致微泡从55888个显著减少到18237个;相应地,仅记录到120个HITS。如较低的HITS计数所示,在常规CABG的ECC中集成的DBT可有效减少气泡,从而保护脑血管系统免受微栓塞。