Su Ho-Ming, Lin Tsung-Hsien, Voon Wen-Chol, Lee Kun-Tai, Chu Chih-Sheng, Yen Hsueh-Wei, Lai Wen-Ter, Sheu Sheng-Hsiung
Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University, Chung-Ho Memorial Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Echocardiography. 2007 Mar;24(3):252-7. doi: 10.1111/j.1540-8175.2007.00382.x.
The aim of this study is to correlate Tei index obtained from tissue Doppler echocardiography (TDE-Tei index) defined as the ratio of the sum of isovolumetric contraction time (ICT) and isovolumetric relaxation time (IRT) over the ejection time (ET) with invasive measurements of left ventricular (LV) performance.
Thirty-four patients who underwent an echocardiographic examination and cardiac catheterization were studied. Invasive measurements of peak +dp/dt, peak -dp/dt, and isovolumic relaxation constant of the left ventricle (tau) were obtained from a micromanometer-tipped catheter.
After a multivariate analysis, TDE-Tei index had a negative correlation with ejection fraction (EF) (beta=-0.384, P = 0.046) and positive correlation with tau (beta= 0.397, P = 0.040). ET had a negative correlation with heart rate (beta=-0.446, P = 0.005) and positive correlation with EF (beta= 0.379, P = 0.015). ICT + IRT had a positive correlation with tau (beta= 0.512, P = 0.002). ICT/ET had a negative correlation with EF (beta=-0.657, P < 0.001) and positive correlation with peak early transmitral filling wave velocity (beta= 0.385, P = 0.001). IRT/ET had a positive correlation with tau (beta= 0.402, P = 0.018).
TDE-Tei index exerts a correlation both with accepted indices of LV systolic and diastolic function acquired by cardiac catheterization. Hence, TDE-Tei index is a simple and feasible indicator in assessing overall LV function.
本研究旨在将经组织多普勒超声心动图获得的Tei指数（TDE - Tei指数，定义为等容收缩时间（ICT）与等容舒张时间（IRT）之和与射血时间（ET）的比值）与左心室（LV）功能的有创测量值相关联。
对34例接受超声心动图检查和心导管检查的患者进行研究。通过微测压导管获得左心室的峰值 +dp/dt、峰值 -dp/dt和等容舒张常数（τ）的有创测量值。
多因素分析后，TDE - Tei指数与射血分数（EF）呈负相关（β = -0.384，P = 0.046），与τ呈正相关（β = 0.397，P = 0.040）。ET与心率呈负相关（β = -0.446，P = 0.005），与EF呈正相关（β = 0.379，P = 0.015）。ICT + IRT与τ呈正相关（β = 0.512，P = 0.002）。ICT/ET与EF呈负相关（β = -0.657，P < 0.001），与二尖瓣早期充盈波峰值速度呈正相关（β = 0.385，P = 0.001）。IRT/ET与τ呈正相关（β = 0.402，P = 0.018）。
TDE - Tei指数与通过心导管检查获得的公认的左心室收缩和舒张功能指标均相关。因此，TDE - Tei指数是评估左心室整体功能的一个简单可行的指标。
