Segev Osnat, Abeliovich Aharon, Kushmaro Ariel
The Unit of Environmental Engineering, Faculty of Engineering Sciences, Ben-Gurion University of the Negev, P.O. Box 653, Be'er-Sheva 84105, Israel.
Chemosphere. 2007 Jun;68(5):958-64. doi: 10.1016/j.chemosphere.2007.01.014. Epub 2007 Feb 20.
Dibromoneopentyl glycol (DBNPG) is a brominated flame retardant that is used as an additive during the manufacture of plastic polymers and as a chemical intermediate for other flame retardants. It is classified as not readily biodegradable and based on experimental studies in animals is believed to be a carcinogen. We have demonstrated, to the best of our knowledge for the first time, the complete biodegradation of DBNPG under aerobic conditions. Total organic carbon (TOC) analysis indicates the complete mineralization of DBNPG. DBNPG biodegradation was accompanied by the release of bromide into the medium, probably due to a biological debromination reaction by bacterial consortia. A denaturing gradient gel electrophoresis (DGGE) analysis of PCR amplified 16S rRNA gene was used, to characterize the bacterial consortia involved in DBNPG biodegradation. At least seven bacterial species were found to be involved in this process, among them species with similarity to strains that are known for their dehalogenating ability.
二溴新戊二醇（DBNPG）是一种溴化阻燃剂，在塑料聚合物制造过程中用作添加剂，并作为其他阻燃剂的化学中间体。它被归类为不易生物降解，基于对动物的实验研究，被认为是一种致癌物。据我们所知，我们首次证明了在有氧条件下DBNPG的完全生物降解。总有机碳（TOC）分析表明DBNPG完全矿化。DBNPG的生物降解伴随着溴化物释放到培养基中，这可能是由于细菌群落的生物脱溴反应。使用PCR扩增的16S rRNA基因的变性梯度凝胶电泳（DGGE）分析来表征参与DBNPG生物降解的细菌群落。发现至少七种细菌物种参与了这一过程，其中一些物种与以脱卤能力而闻名的菌株具有相似性。
