Vohn Rene, Fimm Bruno, Weber Jochen, Schnitker Ralph, Thron Armin, Spijkers Will, Willmes Klaus, Sturm Walter
Clinical Neuropsychology, Department of Neurology, RWTH Aachen University, Aachen, Germany.
Hum Brain Mapp. 2007 Dec;28(12):1267-75. doi: 10.1002/hbm.20350.
In the present study, we were interested in distinguishing the cortical representations of within-modal and cross-modal divided attention tasks by using functional magnetic resonance imaging. Sixteen healthy male subjects aged between 21 and 30 years underwent two within-modal (auditory/auditory, visual/visual) and one cross-modal (auditory/visual) divided attention task, as well as related selective attention control conditions. After subtraction of the corresponding control task the three divided attention tasks, irrespective of sensory modality, revealed significant activation in a predominantly right hemisphere network involving the prefrontal cortex, the inferior parietal cortex, and the claustrum. Under the cross-modal condition, however, the frontal and parietal activation was more extended and more bilateral and there also was stronger right hemisphere activation of the anterior cingulate cortex and the thalamus. In comparison to the within-modal conditions additional bilateral frontal and left inferior parietal activation was found for the cross-modal condition. The supplementary fronto-parietal, anterior cingulate cortex, and thalamus activation in the auditory/visual condition could be argued to reflect an additional demand for coordination of two ongoing cross-modal cognitive processes.
在本研究中，我们感兴趣的是通过功能磁共振成像来区分模态内和跨模态分散注意力任务的皮质表征。16名年龄在21至30岁之间的健康男性受试者接受了两项模态内（听觉/听觉、视觉/视觉）和一项跨模态（听觉/视觉）分散注意力任务，以及相关的选择性注意力控制条件。在减去相应的控制任务后，这三项分散注意力任务，无论感觉模态如何，均在一个主要涉及前额叶皮质、顶下皮质和屏状核的右半球网络中显示出显著激活。然而，在跨模态条件下，额叶和顶叶的激活范围更广且更具双侧性，并且前扣带回皮质和丘脑的右半球激活也更强。与模态内条件相比，跨模态条件下还发现了额外的双侧额叶和左侧顶下皮质激活。听觉/视觉条件下补充性的额顶叶、前扣带回皮质和丘脑激活可以被认为反映了对两个正在进行的跨模态认知过程进行协调的额外需求。
