van der Rhee H J, de Vries E, Coebergh J W W
HagaZiekenhuis, locatie Leyenburg, afd. Dermatologie, Leyweg 275, 2545 CH Den Haag.
Ned Tijdschr Geneeskd. 2007 Jan 13;151(2):118-22.
The negative effects of sunlight include the more frequent or earlier development of skin cancer and degenerative changes in the skin, and the occurrence ofphotodermatoses. - However, sunlight also has a favourable effects; specifically, it may inhibit the development and progression of diseases of the bones, muscles and skin, ofvarious malignancies (carcinoma of the prostate, breast, colon and ovary, non-Hodgkin lymphoma), and may prevent certain autoimmune diseases, particularly multiple sclerosis. - This protective effect is ascribed to an increased synthesis of vitamin D, which is important for bone metabolism and is also able to regulate cell proliferation and differentiation, apoptosis, tumour invasion and angiogenesis. - The possible consequence of this new information is that public information regarding exposure to sunlight must continue to include a warning against excessive exposure to the sun, while at the same time stimulating regular although limited sunbathing.
阳光的负面影响包括皮肤癌更频繁发生或更早出现、皮肤退行性变化以及光皮肤病的发生。——然而，阳光也有有益的作用；具体而言，它可能抑制骨骼、肌肉和皮肤疾病、各种恶性肿瘤（前列腺癌、乳腺癌、结肠癌和卵巢癌、非霍奇金淋巴瘤）的发展和进展，并可能预防某些自身免疫性疾病，尤其是多发性硬化症。——这种保护作用归因于维生素D合成增加，维生素D对骨骼代谢很重要，还能够调节细胞增殖和分化、细胞凋亡、肿瘤侵袭和血管生成。——这一新信息可能带来的结果是，关于阳光照射的公共信息必须继续包括对过度日晒的警告，同时鼓励定期但适度地进行日光浴。
