Bremer Andrew A, Feldman Brian J, Iezza Gioia, Clark Orlo H, Rosenthal Stephen M
Department of Pediatrics, University of California, San Francisco, California, USA.
Thyroid. 2007 Feb;17(2):175-8. doi: 10.1089/thy.2006.0214.
Thyroid nodules are rare in children compared to adults. Although most thyroid nodules are benign, the risk of malignancy is greater in pediatric patients. Papillary and follicular cell tumors account for the majority of thyroid neoplasms; Hürthle cell tumors account for less than 5%. Despite being uncommon, malignant Hürthle cell tumors are potentially more aggressive than papillary and follicular cell tumors. Therefore, distinguishing between types of thyroid neoplasms in a timely fashion has implications for prognosis and therapy. We describe a 12-year-old peripubertal girl who presented with a large right-sided thyroid nodule that was subsequently diagnosed as a Hürthle cell adenoma. To our knowledge, she represents the youngest patient with a Hürthle cell neoplasm.
与成人相比，儿童甲状腺结节较为罕见。虽然大多数甲状腺结节是良性的，但儿科患者发生恶性病变的风险更高。乳头状和滤泡状细胞肿瘤占甲状腺肿瘤的大多数；许特耳细胞肿瘤占比不到5%。尽管罕见，但恶性许特耳细胞肿瘤可能比乳头状和滤泡状细胞肿瘤更具侵袭性。因此，及时区分甲状腺肿瘤的类型对预后和治疗具有重要意义。我们描述了一名12岁青春期前女孩，她出现了一个右侧大甲状腺结节，随后被诊断为许特耳细胞腺瘤。据我们所知，她是最年轻的患有许特耳细胞肿瘤的患者。
