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镓闪烁扫描术在检测恶性软组织肿瘤中的效能。

The efficacy of gallium scintigraphy in detecting malignant soft tissue neoplasms.

作者信息

Schwartz H S, Jones C K

机构信息

Department of Orthopaedics and Rehabilitation, Vanderbilt University, Nashville, Tennessee 37232-2550.

出版信息

Ann Surg. 1992 Jan;215(1):78-82. doi: 10.1097/00000658-199201000-00011.

DOI:10.1097/00000658-199201000-00011
PMID:1731652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1242373/
Abstract

A prospective study was conducted on 55 consecutive patients to evaluate the efficacy of gallium scintigraphy in detecting malignancy in any soft tissue mass. It was determined that gallium scintigraphy could detect malignancy with a sensitivity of 96% and a specificity of 87%. Large and small sarcomas, irrespective of their fascial location, were identifiable by gallium imaging. Occult, nonpulmonary sites of disseminated disease were detected in 13%. Gallium scintigraphy proved to be a reliable predictor of malignancy for all soft tissue masses, but because of its cost, it must be used judiciously.

摘要

对55例连续患者进行了一项前瞻性研究,以评估镓闪烁扫描在检测任何软组织肿块恶性肿瘤方面的疗效。结果确定,镓闪烁扫描检测恶性肿瘤的敏感性为96%,特异性为87%。无论筋膜位置如何,大小肉瘤均可通过镓成像识别。13%的患者检测到隐匿性、非肺部的播散性疾病部位。镓闪烁扫描被证明是所有软组织肿块恶性肿瘤的可靠预测指标,但由于其成本,必须谨慎使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe28/1242373/1dde5a103338/annsurg00083-0103-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe28/1242373/a45f432422b5/annsurg00083-0103-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe28/1242373/1dde5a103338/annsurg00083-0103-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe28/1242373/a45f432422b5/annsurg00083-0103-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe28/1242373/1dde5a103338/annsurg00083-0103-b.jpg

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本文引用的文献

1
The clinical value of bone and gallium scintigraphy for soft-tissue sarcomas of the extremities.骨与镓闪烁扫描术在四肢软组织肉瘤中的临床价值。
J Bone Joint Surg Am. 1984 Mar;66(3):319-27.
2
Gallium-67 localization in lysosomal-like granules of leukemic and nonleukemic murine tissues.镓-67在白血病和非白血病小鼠组织的溶酶体样颗粒中的定位。
J Natl Cancer Inst. 1971 May;46(5):941-52.
3
Scintigraphy with gallium-67 citrate in staging of soft-tissue sarcomas of the extremity.用枸橼酸镓-67进行闪烁扫描在肢体软组织肉瘤分期中的应用。
J Bone Joint Surg Am. 1987 Jul;69(6):886-91.
4
The value of 67Ga scintigraphy in soft-tissue sarcoma and chondrosarcoma.67镓闪烁扫描术在软组织肉瘤和软骨肉瘤中的价值。
Radiology. 1977 Apr;123(1):131-4. doi: 10.1148/123.1.131.
5
Studies on gallium accumulation in inflammatory lesions: I. Gallium uptake by human polymorphonuclear leukocytes.炎症病灶中镓蓄积的研究:I. 人多形核白细胞对镓的摄取
J Nucl Med. 1978 Jan;19(1):36-43.
6
The association of Ga-67 and lactoferrin.镓-67与乳铁蛋白的关联。
J Nucl Med. 1977 Jul;18(7):713-7.
7
Scintigraphic evaluation of sarcomata in children and adults by Ga67 citrate.用枸橼酸镓67对儿童和成人肉瘤进行闪烁扫描评估。
Cancer. 1978 Oct;42(4):1760-5. doi: 10.1002/1097-0142(197810)42:4<1760::aid-cncr2820420414>3.0.co;2-8.