Edeling C J
Clin Nucl Med. 1983 May;8(5):205-9. doi: 10.1097/00003072-198305000-00004.
One hundred sixty-nine children suspected of having malignant disease were examined by Ga-67 scintigraphy. In 99 children with untreated diseases at the time of examination, abnormal accumulation of Ga-67 was found in 51 patients, including 40 with malignant tumor. Forty-three negative results were obtained in children with benign disorders. Five false-negative results were obtained in patients with neuroblastoma of the adrenal gland. In 70 children with malignant diseases treated before the examination, abnormal accumulation of Ga-67 was seen in 40 patients, including 38 with malignant disease and two with no clinical evidence of recurrence. Normal results were obtained in 30 patients, including 11 still suffering from malignant disease. The results of Ga-67 scintigraphy in all of the children were evaluated qualitatively. For the final diagnosis of malignant disease, diagnostic specificity was 86% and diagnostic sensitivity 79%. The prevalence of malignant disease was 56%. It is concluded that Ga-67 scintigraphy should be used for primary visualization and control of malignant tumors in children.
对169名疑似患有恶性疾病的儿童进行了镓-67闪烁扫描检查。在检查时99名患有未经治疗疾病的儿童中，51名患者发现镓-67异常聚集，其中40名患有恶性肿瘤。患有良性疾病的儿童中有43例结果为阴性。肾上腺神经母细胞瘤患者中有5例假阴性结果。在70名检查前接受过恶性疾病治疗的儿童中，40名患者可见镓-67异常聚集，其中38名患有恶性疾病，2名无复发的临床证据。30名患者结果正常，其中11名仍患有恶性疾病。对所有儿童的镓-67闪烁扫描结果进行了定性评估。对于恶性疾病的最终诊断，诊断特异性为86%，诊断敏感性为79%。恶性疾病的患病率为56%。结论是镓-67闪烁扫描应用于儿童恶性肿瘤的初步显像和监测。
