Cucinotta D
Department of Internal Medicine and Aging, S. Orsola-Malpighi University Hospital, Via Albertoni, 15, 40138 Bologna, Italy.
Arch Gerontol Geriatr. 2007;44 Suppl 1:125-32. doi: 10.1016/j.archger.2007.01.019.
Parallel with global trends in population aging, numerous check-up programs of anti-aging purposes have been developed and implemented. Healthy aging and active aging are goals of the United Nations Research Agenda on Aging for the 21th century. It is necessary to have a lifelong process optimizing opportunities for improving and preserving health, physical, social and mental wellness, independence, quality of life and activity. An anti-aging check-up should point out to the factors that lead to functional decline, shifting the outcome measurement to focus on those persons who are aging well, to improve wellness. This paper discusses the principal factors of pathological aging: nutrition, physical activity, hormones, inflammation, depression, ecology and social/behavioral factors. A model of assessment is proposed based on clinical, functional and biological parameters.
随着全球人口老龄化趋势的发展，许多旨在抗衰老的体检项目已被开发和实施。健康老龄化和积极老龄化是联合国21世纪老龄问题研究议程的目标。有必要通过一个终身过程来优化改善和保持健康、身体、社会和心理健康、独立性、生活质量及活动能力的机会。抗衰老体检应指出导致功能衰退的因素，将结果测量的重点转向那些衰老状况良好的人，以改善健康状况。本文讨论了病理性衰老的主要因素：营养、体育活动、激素、炎症、抑郁、生态以及社会/行为因素。基于临床、功能和生物学参数提出了一种评估模型。
