Boekschoten M V, van Cruchten S T J, Kosmeijer-Schuil T G, Katan M B
Wageningen Universiteit, afd. Humane Voeding, Bomenweg 2, 6703 HD Wageningen.
Ned Tijdschr Geneeskd. 2006 Dec 30;150(52):2873-5.
To determine the amounts of the serum-cholesterol raising diterpenes cafestol and kahweol in coffee made with coffee pads and the Senseo coffee machine as opposed to filtered and unfiltered coffee.
Observational.
In five cities in the Netherlands coffee was purchased in three major supermarkets resulting in a total of 30 samples of coffee pads. The levels of cafestol and kahweol were determined by gas chromatography. As controls, the diterpene levels in filtered and unfiltered coffee were also measured.
Coffee prepared using coffee pads contained on average 0.76 mg/l cafestol (95% CI: 0.69-0.82) and 0.85 mg/l kahweol (95% CI: 0.77-0.94). Filtered coffee contained 0.76 mg/l cafestol (95% CI: 0.63-0.88) and 0.81 mg/l kahweol (95% CI: 0.63-0.99). Unfiltered coffee contained 72.5 mg/l cafestol (95% CI: 48.5-96.4) and 71.5 mg/l kahweol (95% CI: 45.0-98.1).
Coffee prepared using coffee pads and the Senseo coffee machine contained minute levels of diterpenes comparable to those of filtered coffee. Its effect on serum-cholesterol levels is therefore likely to be negligible.
测定用咖啡包和Senseo咖啡机制作的咖啡中，相比于过滤咖啡和未过滤咖啡，会升高血清胆固醇的二萜类物质咖啡醇和咖啡豆醇的含量。
观察性研究。
在荷兰的五个城市，从三家大型超市购买咖啡，共获得30份咖啡包样品。采用气相色谱法测定咖啡醇和咖啡豆醇的含量。作为对照，还测定了过滤咖啡和未过滤咖啡中二萜类物质的含量。
用咖啡包制作的咖啡中，咖啡醇平均含量为0.76毫克/升（95%置信区间：0.69 - 0.82），咖啡豆醇平均含量为0.85毫克/升（95%置信区间：0.77 - 0.94）。过滤咖啡中咖啡醇含量为0.76毫克/升（95%置信区间：0.63 - 0.88），咖啡豆醇含量为0.81毫克/升（95%置信区间：0.63 - 0.99）。未过滤咖啡中咖啡醇含量为72.5毫克/升（95%置信区间：48.5 - 96.4），咖啡豆醇含量为71.5毫克/升（95%置信区间：45.0 - 98.1）。
用咖啡包和Senseo咖啡机制作的咖啡中二萜类物质含量极低，与过滤咖啡相当。因此，其对血清胆固醇水平的影响可能微不足道。
