Goldberg Aaron D, Allis C David, Bernstein Emily
Laboratory of Chromatin Biology, The Rockefeller University, New York, NY 10021, USA.
Cell. 2007 Feb 23;128(4):635-8. doi: 10.1016/j.cell.2007.02.006.
Epigenetics has recently evolved from a collection of diverse phenomena to a defined and far-reaching field of study. In this Essay, we examine the epistemology of epigenetics, provide a brief overview of underlying molecular mechanisms, and suggest future challenges for the field.
表观遗传学最近已从一系列不同的现象发展成为一个明确且影响深远的研究领域。在本文中,我们探讨表观遗传学的认识论,简要概述其潜在的分子机制,并提出该领域未来面临的挑战。