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嗜酸微球菌所致脑脓肿:首例病例报告

Brain abscess due to Streptococcus acidominimus: first case report.

作者信息

Cone Lawrence A, Etebar Shahin, Waterbor Robert B

机构信息

Department of Medicine, Eisenhower Medical Center, Rancho Mirage, CA 92270, USA.

出版信息

Surg Neurol. 2007 Mar;67(3):296-7. doi: 10.1016/j.surneu.2006.06.062.

DOI:10.1016/j.surneu.2006.06.062
PMID:17320642
Abstract

BACKGROUND

Streptococcus acidominimus resembles Streptococcus viridans, but they can now be differentiated by phenotypic studies. Only a single previous case of pneumonia, pericarditis, and meningitis has been reported.

CASE DESCRIPTION

We recently encountered a patient with brain abscess from which S acidominimus was isolated after initially being recorded as S viridans. Because 49% of all S viridans isolated from abscesses are resistant to beta-lactam antimicrobials, speciation is important as well as in vitro sensitivity testing. Streptococcus acidominimus is ordinarily sensitive to beta-lactams, and the use of ceftriaxone for 6 weeks successfully resulted in cure of the brain abscess.

CONCLUSION

The use of speciation in treatment of S viridans should improve clinical outcomes.

摘要

背景

嗜酸微球菌与草绿色链球菌相似,但现在可通过表型研究加以区分。此前仅报道过一例肺炎、心包炎和脑膜炎病例。

病例描述

我们最近遇到一名脑脓肿患者,最初被记录为草绿色链球菌,后从中分离出嗜酸微球菌。由于从脓肿中分离出的所有草绿色链球菌中有49%对β-内酰胺类抗菌药物耐药,菌种鉴定以及体外药敏试验都很重要。嗜酸微球菌通常对β-内酰胺类敏感,使用头孢曲松治疗6周成功治愈了脑脓肿。

结论

在草绿色链球菌治疗中进行菌种鉴定应能改善临床结果。

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