SurePath液体保存剂和Digene宫颈采样器标本中的巴氏细胞病理学及高危型人乳头瘤病毒的存在情况

Pap cytopathology and the presence of high-risk human papillomavirus in SurePath liquid preservative and Digene cervical sampler specimens.

作者信息

Kapala Julius, Jang Dan, Patel Jay, Biers Kathleen, Smieja Marek, Chernesky Max

机构信息

Gamma-Dynacare Medical Laboratories, Brampton, Ont., Canada.

出版信息

J Virol Methods. 2007 Jun;142(1-2):223-5. doi: 10.1016/j.jviromet.2007.01.028. Epub 2007 Feb 23.

DOI:10.1016/j.jviromet.2007.01.028

PMID:17320978

Abstract

The Digene Hybrid Capture 2 (HC2) assay for high-risk human papillomavirus (HPV) identified 92 (28.7%) infected women by testing 320 SurePath liquid-based Pap samples and a hybrid capture 2 (HC2) sampler collection. HPV positivity was predictive for high-grade lesions. A majority of women had normal cervical readings although 15.8% were HPV-positive. Half of the patients with a reading of atypical squamous cells of undetermined significance (ASCUS) (n=16) were HPV-positive.

摘要

用于检测高危型人乳头瘤病毒（HPV）的Digene杂交捕获2代（HC2）检测法，通过对320份SurePath液基巴氏样本和一个杂交捕获2代（HC2）采样收集器进行检测，确定了92名（28.7%）受感染女性。HPV阳性可预测高级别病变。尽管15.8%的女性HPV呈阳性，但大多数女性的宫颈检测结果正常。非典型鳞状细胞意义不明确（ASCUS）检测结果的患者中有一半（n = 16）HPV呈阳性。