Wang Zhiheng, Willett Christopher G, Yin Fang-Fang
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.
Int J Radiat Oncol Biol Phys. 2007 May 1;68(1):259-66. doi: 10.1016/j.ijrobp.2006.11.057. Epub 2007 Feb 22.
To investigate whether the effect of organ motion can be further reduced with the application of a cardiac gating technique, together with respiratory gating.
Axial and coronal images through the heart and liver were continuously scanned with fast cine magnetic resonance imaging scans at three different gating settings: (1) without respiratory and cardiac gating; (2) with respiratory gating, but without cardiac gating; and (3) with both respiratory and cardiac gating. The effect of motion for either the heart or liver was analyzed with probability maps.
With the application of respiratory gating only, the marginal region on the probability map was reduced by 10.0% in the axial slice and 19.8% in the coronal slice for the heart. It was reduced by 5.2% in the axial slice and 20.8% in the coronal slice for the liver. With the application of cardiac gating together with respiratory gating, the marginal region on the probability map was reduced further. The reduction was 8.0% in the axial slice and 13.6% in the coronal slice for the heart and 5.9% in the axial slice and 7.0% in the coronal slice for the liver.
The effect of organ motion can be further reduced with the application of cardiac gating together with respiratory gating. The potential application to treatment planning merits further investigation.
研究应用心脏门控技术结合呼吸门控是否能进一步降低器官运动的影响。
通过心脏和肝脏的轴向及冠状位图像，采用快速电影磁共振成像扫描在三种不同的门控设置下进行连续扫描：（1）无呼吸和心脏门控；（2）有呼吸门控但无心脏门控；（3）有呼吸和心脏门控。利用概率图分析心脏或肝脏运动的影响。
仅应用呼吸门控时，心脏在轴向层面概率图的边缘区域减少了10.0%，在冠状层面减少了19.8%。肝脏在轴向层面减少了5.2%，在冠状层面减少了20.8%。同时应用心脏门控和呼吸门控时，概率图的边缘区域进一步减少。心脏在轴向层面减少了8.0%，在冠状层面减少了13.6%；肝脏在轴向层面减少了5.9%，在冠状层面减少了7.0%。
应用心脏门控结合呼吸门控可进一步降低器官运动的影响。其在治疗计划中的潜在应用值得进一步研究。
