Krieg A H, Hefti F
1Orthopaedic Department Children's Hospital, University of Basel (UKBB), P O Box 4005, Basel, Switzerland.
J Bone Joint Surg Br. 2007 Feb;89(2):215-21. doi: 10.1302/0301-620X.89B2.17686.
We evaluated 31 patients who were treated with a non-vascularised fibular graft after resection of primary musculoskeletal tumours, with a median follow-up of 5.6 years (3 to 26.7 years). Primary union was achieved in 89% (41 of 46) of the grafts in a median period of 24 weeks. All 25 grafts in 18 patients without additional chemotherapy and/or radiotherapy achieved primary union, compared with 16 of the 21 grafts (76%; 13 patients) with additional therapy (p=0.017). Radiographs showed an increase in diameter in 70% (59) of the grafts. There were seven fatigue fractures in six patients, but only two needed treatment. Non-vascularised fibular transfer is a simpler, less expensive and a shorter procedure than the use of vascularised grafts and allows remodelling of the fibula at the donor site. It is a biological reconstruction with good long-term results, and a relatively low donor site complication rate of 16%.
我们评估了31例在原发性肌肉骨骼肿瘤切除术后接受非血管化腓骨移植的患者,中位随访时间为5.6年(3至26.7年)。89%(46例中的41例)的移植骨在中位24周时实现了一期愈合。18例未接受额外化疗和/或放疗患者的25例移植骨均实现了一期愈合,相比之下,接受额外治疗的21例移植骨中的16例(76%;13例患者)实现了一期愈合(p = 0.017)。X线片显示70%(59例)的移植骨直径增加。6例患者出现7例疲劳骨折,但仅2例需要治疗。与使用血管化移植骨相比,非血管化腓骨移植是一种更简单、成本更低且手术时间更短的方法,并且允许供区腓骨重塑。这是一种具有良好长期效果的生物学重建方法,供区并发症发生率相对较低,为16%。