Alemayehu Elsa Daniel, Kebede Eskinder
Department of Orthopedic Surgery and Trauma, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia.
Orthop Res Rev. 2023 Jun 3;15:119-127. doi: 10.2147/ORR.S402927. eCollection 2023.
Giant Cell tumors (GCT) are benign tumors with aggressive characteristics and the potential to metastasize. These are seldom lethal benign bone tumors but are associated with massive local bony architecture distraction making their treatment difficult, especially if found in peri-articular locations. Several long bone giant cell tumor (GCT) cases have been reported. We report a unique treatment of distal femur GCT in a 19-year-old in a resource-limited setup whose initial presentation was following a pathologic fracture. We used a staged surgical protocol. In the first stage, distal femur resection and implantation of poly methyl methacrylate (PMMA) cement spacer for induced membrane formation was done, followed by SIGN nail and non-vascularized fibula strut graft. There was adequate healing and no recurrence was noted during the two-year follow-up.
骨巨细胞瘤(GCT)是具有侵袭性特征且有转移潜能的良性肿瘤。这些是很少致命的良性骨肿瘤,但与局部大量骨质结构破坏相关,使其治疗困难,尤其是在关节周围部位发现时。已有多例长骨骨巨细胞瘤(GCT)病例报道。我们报告了一名19岁患者在资源有限的情况下远端股骨GCT的独特治疗,其最初表现为病理性骨折。我们采用了分期手术方案。在第一阶段,进行了远端股骨切除并植入聚甲基丙烯酸甲酯(PMMA)骨水泥间隔物以诱导膜形成,随后使用SIGN钉和非血管化腓骨支撑移植。愈合良好,在两年随访期间未发现复发。