Suppr超能文献

非血管化腓骨支撑植骨的生存能力及临床疗效增强:621例患者50年经验总结

Enhanced Viability and Clinical Outcomes of Non-vascularized Fibular Strut Grafts: a 50-Year Experience of 621 Cases.

作者信息

Yadav Surender Singh

机构信息

Mirpur Institute of Medical Sciences, Mirpur, Distt., Rewari, Haryana India.

出版信息

Indian J Orthop. 2025 Mar 21;59(5):581-590. doi: 10.1007/s43465-024-01313-1. eCollection 2025 May.

Abstract

AIMS

Non-vascularised fibular grafts have been used for over a century as means of reconstruction the skeletal defects. The aim of this study was to evaluate the viability and clinical outcomes of non-vascularized fibular strut grafts using an immediate fixation technique. This enables them to retain their viability for early incorporation with the host-bone.

MATERIALS AND METHODS

During the last 5 decades, 621 cases of bone gaps have been managed with non-vascularised fibular struts in various clinical situations. Out of these 498 cases were after excision of bone tumours, 90 post-infective gaps and 33 post-traumatic. According to the site of the defect, single fibular struts were used in 115 cases, twin grafts in 493 and triple struts in 13 cases. The size of the graft measured from 5 to 25 cms.

RESULTS

Functional results have been evaluated according to the Clinical and Radiological score. The biological activity resulting in union and hypertrophy of the twin and triple struts demonstrated the viability of the grafts in 91% cases. Evidence of radiological non-union at one of the host-graft junctions resulted in 39 cases. Stress fractures had been observed in 22 cases only in single grafts and none in twin or triple grafts.

CONCLUSION

The technique of immediate fixation of non-vascularized fibular grafts at the host site appears to have changed the age-old concept regarding the non-vascularised grafts. The results have revealed that such struts retain their osteogenic cells and remain viable resulting in 'lateral-union' and unite with the host bone without undergoing the classical degenerative changes.

LEVEL OF EVIDENCE

IV.

摘要

目的

无血管腓骨移植作为修复骨骼缺损的方法已应用了一个多世纪。本研究的目的是评估采用即刻固定技术的无血管腓骨支撑移植的存活情况及临床效果。这能使它们保持存活以早期与宿主骨融合。

材料与方法

在过去50年里,621例骨缺损病例在各种临床情况下采用了无血管腓骨支撑移植进行治疗。其中498例是骨肿瘤切除术后,90例是感染后骨缺损,33例是创伤后骨缺损。根据缺损部位,115例使用单根腓骨支撑,493例使用双根移植,13例使用三根支撑。移植骨长度为5至25厘米。

结果

根据临床和影像学评分评估功能结果。双根和三根支撑移植骨融合及肥大所产生的生物学活性表明91%的病例中移植骨存活。在宿主 - 移植骨交界处之一出现影像学骨不连的有39例。仅在单根移植中观察到22例应力性骨折,双根或三根移植中未观察到。

结论

在宿主部位即刻固定无血管腓骨移植的技术似乎改变了关于无血管移植的古老观念。结果显示,此类支撑物保留其成骨细胞并保持存活,从而实现“侧方融合”并与宿主骨融合,而不发生典型的退变改变。

证据级别

IV级。

相似文献

4
Vascularized versus Nonvascularized Bone Grafts: What Is the Evidence?带血管骨移植与不带血管骨移植:证据何在?
Clin Orthop Relat Res. 2016 May;474(5):1319-27. doi: 10.1007/s11999-016-4769-4. Epub 2016 Mar 1.

本文引用的文献

6
Vascularized fibula transfer for lower limb reconstruction.带血管腓骨移植在下肢重建中的应用。
Microsurgery. 2011 Mar;31(3):205-11. doi: 10.1002/micr.20841. Epub 2011 Feb 25.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验