Bidaguren A, Müller-Thyssen A, Blanco A, Mendicute J, Ubeda M
Servicio de Oftalmología, Hospital Donostia, San Sebastián (Guipúzcoa), España.
Arch Soc Esp Oftalmol. 2007 Feb;82(2):109-12. doi: 10.4321/s0365-66912007000200009.
We report the case of a 76-year-old woman who attended our hospital because of a sudden loss of visual acuity in her left eye. The problem appeared to be that of retrobulbar optic neuritis. However, the age of the patient together with the simultaneous use of Infliximab to treat her rheumatoid arthritis, suggests the demyelination may have been associated with the Infliximab use.
TNFa inhibitors (including Infliximab) are associated with demyelinating diseases including optic neuritis.
我们报告了一名76岁女性的病例,她因左眼突然视力丧失前来我院就诊。问题似乎是球后视神经炎。然而,患者的年龄以及同时使用英夫利昔单抗治疗类风湿性关节炎,提示脱髓鞘可能与使用英夫利昔单抗有关。
肿瘤坏死因子α抑制剂(包括英夫利昔单抗)与包括视神经炎在内的脱髓鞘疾病有关。