Rheumatol Int. 2013 Apr;33(4):1101-3. doi: 10.1007/s00296-011-2316-x. Epub 2011 Dec 25.
Demyelinating diseases were described in patients receiving anti-TNF agents. Optic neuritis (ON) induced by TNF blockers was already described in 22 cases in the literature. In this article, the authors report a 53-year-old woman with refractory rheumatoid arthritis that developed neuritis optica after the fourth dose of infliximab and had a good outcome after anti-TNF withdrawal, associated with glucocorticoid treatment. In addition, the previous cases of ON induced by anti-TNF agents were reviewed.
脱髓鞘疾病在接受抗 TNF 药物治疗的患者中已有描述。TNF 阻滞剂引起的视神经炎（ON）在文献中已描述过 22 例。本文作者报道了 1 例 53 岁女性，患有难治性类风湿关节炎，在接受第四次英夫利昔单抗治疗后发生视神经炎，停用 TNF 拮抗剂并联合糖皮质激素治疗后病情好转。此外，还回顾了先前抗 TNF 药物引起的 ON 病例。
