Burbridge Jennifer A, Barch Deanna M
Department of Psychology, Washington University, USA.
J Abnorm Psychol. 2007 Feb;116(1):30-42. doi: 10.1037/0021-843X.116.1.30.
Research shows that individuals with schizophrenia report symptoms of anhedonia when assessed by interview or questionnaire. However, when presented with emotional stimuli, they report emotional experiences that are similar to those of control participants. The authors hypothesized that deficits in working memory and episodic memory contribute to such discrepancies. They administered measures of working and episodic memory, self-report anhedonia questionnaires, and several types of emotional stimuli to 49 individuals with schizophrenia and 47 control participants. All participants reported experiencing similar amounts of pleasant-unpleasant emotion (valence) in response to stimuli, but individuals with schizophrenia reported experiencing less arousal for negative stimuli. Individuals with schizophrenia also reported greater social and physical anhedonia on a traditional anhedonia questionnaire. Disturbances in working memory moderated the relationship between physical anhedonia and participants' emotional experience of positive stimuli.
研究表明，通过访谈或问卷调查评估时，精神分裂症患者会报告快感缺乏症状。然而，当面对情感刺激时，他们报告的情感体验与对照组参与者相似。作者推测，工作记忆和情景记忆的缺陷导致了这种差异。他们对49名精神分裂症患者和47名对照参与者进行了工作记忆和情景记忆测试、自我报告快感缺乏问卷以及几种情感刺激测试。所有参与者报告在面对刺激时体验到的愉快-不愉快情绪（效价）量相似，但精神分裂症患者报告对负面刺激的唤醒程度较低。在传统的快感缺乏问卷中，精神分裂症患者还报告有更强的社交和身体快感缺乏。工作记忆障碍调节了身体快感缺乏与参与者对积极刺激的情感体验之间的关系。
