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性病性淋巴肉芽肿:老病原体,新故事。

Lymphogranuloma venereum: old pathogen, new story.

机构信息

Bureau of Sexually Transmitted Disease Control, New York City Department of Health and Mental Hygiene, 125 Worth Street, Room 207, CN 73, New York, NY 10013, USA.

出版信息

Curr Infect Dis Rep. 2007 Mar;9(2):143-50. doi: 10.1007/s11908-007-0010-7.

DOI:10.1007/s11908-007-0010-7
PMID:17324352
Abstract

Lymphogranuloma venerum (LGV), an ulcerative sexually transmitted infection caused by the L serovars of Chlamydia trachomatis, has gained recent attention as a cause of hemorrhagic proctitis among men who have sex with men in North America, the United Kingdom, and Europe. It has been a rare diagnosis, and likely has not been included in the routine differential diagnosis for proctocolitis. The lack of a specific diagnostic test has complicated LGV case ascertainment. In the absence of laboratory confirmation of L serovars, physicians are advised to treat possible cases presumptively for LGV and provide medical management of sexual partners. The appearance of an ulcerative infection in sexual networks with high rates of HIV coinfection may forewarn of increased HIV transmission; interruption of disease transmission remains a priority for medical providers and the public health community.

摘要

性病性淋巴肉芽肿(LGV)是由沙眼衣原体 L 血清型引起的溃疡性性传播感染,最近在北美、英国和欧洲的男男性行为人群中引起了人们对出血性直肠炎的关注。这是一种罕见的诊断,可能未被包括在直肠结肠炎的常规鉴别诊断中。缺乏特定的诊断测试使 LGV 病例的确定变得复杂。在没有实验室确认 L 血清型的情况下,建议医生根据疑似病例进行 LGV 治疗,并对性伴侣进行医疗管理。在 HIV 合并感染率高的性网络中出现溃疡性感染,可能预示着 HIV 传播的增加;中断疾病传播仍然是医疗提供者和公共卫生界的首要任务。

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Discovering and differentiating new and emerging clonal populations of Chlamydia trachomatis with a novel shotgun cell culture harvest assay.通过一种新型鸟枪法细胞培养收获测定法发现并区分沙眼衣原体新出现的克隆群体。
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