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使用放射性标记和未放射性标记的聚乙烯醇海绵对一名遗传性出血性毛细血管扩张症患者的肝动静脉畸形进行栓塞治疗:病例报告

Embolization of hepatic arteriovenous malformations using radiolabeled and nonradiolabeled polyvinyl alcohol sponge in a patient with hereditary hemorrhagic telangiectasia: case report.

作者信息

Whiting J H, Morton K A, Datz F L, Patch G G, Miller F J

机构信息

Department of Radiology, University of Utah School of Medicine, Salt Lake City.

出版信息

J Nucl Med. 1992 Feb;33(2):260-2.

PMID:1732452
Abstract

Polyvinyl alcohol sponge (PVA) radiolabeled with 99mTc-sulfur colloid was used to evaluate a large hepatic arteriovenous malformation (AVM) in a 71-yr-old white female prior to embolization. The patient had hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu) with severe left-to-right shunting through the hepatic AVM which resulted in high-output congestive heart failure. The patient also had severe pulmonary hypertension. Scintigraphic imaging of the embolized radiolabeled PVA particles allowed us to be certain that the particles did not flow through the liver and inadvertently embolize the lungs; with the patient's already poor pulmonary status, embolization could have been fatal.

摘要

用99mTc-硫胶体标记的聚乙烯醇海绵(PVA)在栓塞前用于评估一名71岁白人女性的巨大肝动静脉畸形(AVM)。该患者患有遗传性出血性毛细血管扩张症(奥斯勒-韦伯-伦杜综合征),通过肝AVM存在严重的左向右分流,导致高输出量充血性心力衰竭。患者还患有严重的肺动脉高压。对栓塞的放射性标记PVA颗粒进行闪烁成像,使我们能够确定颗粒没有流经肝脏并意外栓塞肺部;鉴于患者已经很差的肺部状况,栓塞可能是致命的。

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