Kozlowski H, Yrabowska M
Arch Geschwulstforsch. 1975;45(2):163-72.
Within the tissue proteins in stroma of breast cancer occured multifocal elastotic transformations. The transformations concern collagen bundles that are devoided of mucopolysaccharide substance. The fields of degenerated connective tissue take on the capacities to dye like elastic fibres. The authors suggest that the increase of elastotic material in stroma of breast cancer is bound with the collagen degradation that is caused by metabolites of cancer tissue. The phenomenon occured in all age groups and is not closely bound with the grade of histological malignancy of cancer.
在乳腺癌基质的组织蛋白中发生了多灶性弹性变性转变。这些转变涉及缺乏粘多糖物质的胶原束。退化的结缔组织区域具有像弹性纤维一样染色的能力。作者认为,乳腺癌基质中弹性物质的增加与癌组织代谢产物引起的胶原降解有关。这种现象发生在所有年龄组,并且与癌症的组织学恶性程度没有密切关系。