Kim Sung Ai, Lee Jin Hyoung, Park Soo Young, Kim Hoguen, Kim Tae Il, Kim Won Ho
Department of Gastroenterology, Yonsei University Medical Center, 134 Sinchon-dong, Seodaemum-gu, 120-752 Seoul, Korea.
Yonsei Med J. 2007 Feb 28;48(1):135-8. doi: 10.3349/ymj.2007.48.1.135.
Early colorectal cancer (ECC) is defined as invasive tumor limited to the colonic and rectal mucosa or submucosa, regardless of the presence or absence of lymph node metastasis. The incidence of lymph node metastasis in ECC ranges from 0 to 15.4%, and risk factors include depth of submucosal invasion, growth patterns (polypoid or non-polypoid), histologic subclassification, and lymphatic invasion. Of non-polypoid growth patterns, the depressed types of colorectal cancer have higher malignant potential than polypoid types, even for small sizes. Unfortunately, this type is also difficult to detect on colonoscopic examination. In this report, we describe a case of depressed type ECC with extensive lymph node metastasis without regional lymph node involvement.
早期结直肠癌（ECC）被定义为局限于结肠和直肠黏膜或黏膜下层的浸润性肿瘤，无论有无淋巴结转移。ECC中淋巴结转移的发生率为0%至15.4%，危险因素包括黏膜下浸润深度、生长方式（息肉样或非息肉样）、组织学亚分类和淋巴管浸润。在非息肉样生长方式中，即使是小尺寸的结直肠癌凹陷型也比息肉样类型具有更高的恶性潜能。不幸的是，这种类型在结肠镜检查中也难以检测到。在本报告中，我们描述了一例凹陷型ECC伴有广泛淋巴结转移但无区域淋巴结受累的病例。
