Han D, Sohn J H, Cho Y J, Jeon Y C, Kim H J, Park K N, Chang S J
College of Medicine, Hanyang University Kun Hospital, Kyunggi-do, Korea.
J Korean Med Sci. 1997 Oct;12(5):465-8. doi: 10.3346/jkms.1997.12.5.465.
A flat depressed early colon cancer (FDEC) is characterized by non-polypoid growth pattern, no association of adenomatous tissues and a tendency of even small lesions toward submucosal invasion and lymph node metastasis. It supports de novo carcinogenesis of colorectal cancer, although most colorectal cancers arise in pre-existing adenoma (adenoma-carcinoma sequence). There have been few reports of small depressed cancers because of the difficulty in colonoscopic detection and the rapid development to ulcerating advanced cancers. We report a case of flat depressed early colon cancer confined to mucosa detected by indigo carmine contrast colonoscopy.
平坦凹陷型早期结肠癌（FDEC）的特征为非息肉样生长模式，无腺瘤组织关联，且即使是小病灶也有向黏膜下浸润和淋巴结转移的倾向。尽管大多数结直肠癌起源于先前存在的腺瘤（腺瘤-癌序列），但它支持结直肠癌的新发致癌机制。由于结肠镜检查难以发现且易迅速发展为溃疡性进展期癌，关于小凹陷型癌的报道很少。我们报告一例经靛胭脂对比结肠镜检查发现的局限于黏膜层的平坦凹陷型早期结肠癌病例。
