Gräter H
Klinik für Onkologie, Gastroenterologie und Allgemeine Innere Medizin, Klinikum Esslingen.
Praxis (Bern 1994). 2007 Jan 31;96(5):145-52. doi: 10.1024/1661-8157.96.5.145.
Gastroesophageal Reflux Disease (GERD) encloses the broad spectrum from simple discomfort to severe illness due to complications. Young people with typical symptoms may be treated without preceding endoscopy. On the other hand esophagogastroscopy ist the most important diagnostic procedure for elderly patients and for those with atypical symptoms. Proton pump inhibitors are the drugs of choice to relieve GERD related symptoms. Anti reflux surgery is an effective alternative for selected patients, whereas endoscopic procedures are not yet fully developped. Since Barrett's esophagus is a precancerous lesion, a surveillance program is recomendable.
胃食管反流病（GERD）涵盖了从单纯不适到因并发症导致的严重疾病的广泛范围。有典型症状的年轻人在没有先行内镜检查的情况下也可接受治疗。另一方面，食管胃镜检查是老年患者和有非典型症状患者最重要的诊断方法。质子泵抑制剂是缓解GERD相关症状的首选药物。抗反流手术是部分选定患者的有效替代方案，而内镜手术尚未完全成熟。由于巴雷特食管是一种癌前病变，推荐进行监测计划。
