Jacques Isabelle, Grayon Maggy, Verger Jean-Michel
UR1282, Unité d'Infectiologie Animale et Santé Publique, Institut National de la Recherche Agronomique, Centre de Tours-Nouzilly, Nouzilly, France.
FEMS Microbiol Lett. 2007 May;270(2):245-9. doi: 10.1111/j.1574-6968.2007.00675.x. Epub 2007 Feb 26.
Since the 1990s, Brucella strains not matching the characteristics of any of the six conventional species have been isolated worldwide from marine mammals. In this study, 31 Brucella strains isolated from various marine mammals were examined for their oxidative metabolic pattern on 12 amino-acid and carbohydrate substrates. Three main oxidative profiles different from those of the Brucella terrestrial mammal strains were identified for the marine mammal strains: one gathering strains isolated from pinnipeds and two gathering strains from cetaceans. Thus, both oxidative metabolism results and previous molecular studies are in agreement with the proposal of two new Brucella species, Brucella pinnipediae and Brucella cetaceae, to classify the Brucella strains isolated from marine mammals, and are also in accordance with a classification of species of the Brucella genus based on host preference.
自20世纪90年代以来，在全球范围内从海洋哺乳动物中分离出了不符合六种传统布鲁氏菌属物种任何特征的菌株。在本研究中，对从各种海洋哺乳动物中分离出的31株布鲁氏菌菌株在12种氨基酸和碳水化合物底物上的氧化代谢模式进行了检测。针对海洋哺乳动物菌株，鉴定出了三种与陆地哺乳动物布鲁氏菌菌株不同的主要氧化谱：一种聚集了从鳍足类动物分离出的菌株，另两种聚集了从鲸类动物分离出的菌株。因此，氧化代谢结果和先前的分子研究均与提出的两个新布鲁氏菌物种——海兽布鲁氏菌和鲸类布鲁氏菌——一致，以便对从海洋哺乳动物中分离出的布鲁氏菌菌株进行分类，并且也符合基于宿主偏好对布鲁氏菌属物种的分类。
