Mulder-Kampinga G A, Boer K, Scherpbier H J
Afd. Virologie, Academisch Medisch Centrum, Amsterdam.
Ned Tijdschr Geneeskd. 1992 Jan 11;136(2):80-4.
A review is given of the pregnant women with HIV infection known to the co-ordinating centre of the 'Dutch prospective study of HIV seropositive pregnant women and their children'. Fifty-five women with 57 pregnancies were discovered between 1 September 1985 and 1 January 1991. Of these women, 60% were not of Dutch origin and 56% were living in Amsterdam. Thirty-two women were (former) intravenous drug users. In 23 women heterosexual transmission was likely; two women were also blood transfusion recipients. Nearly half (11/23) of these women came from, or had a partner from, an AIDS-endemic area. In 16 women HIV seropositivity was known before pregnancy. Twenty-four women were specifically tested during pregnancy or within 1 week after parturition because of risk factors for HIV infection. Fifteen women were discovered in a HIV screening programme of pregnant women in Amsterdam (n = 13) and the University Hospital of Groningen (n = 2). At first, eight of these women did not mention risk factors. Thirty-five women could choose abortion (less than or equal to 20 weeks of gestation); the majority (69%) decided to continue pregnancy. Twelve pregnancies ended in an elective or spontaneous abortion, 39 in the birth of 40 children (one pair of twins) of whom 39 were viable, three women were still pregnant and of three the pregnancy outcome was unknown. Preterm delivery (8/39) and birth weight less than 2500 gram (7/39) were seen frequently, the latter particularly in women (formerly) using intravenous drugs (6/25).
对“荷兰HIV血清阳性孕妇及其子女前瞻性研究”协调中心所知晓的感染HIV的孕妇进行了综述。1985年9月1日至1991年1月1日期间发现了55名妇女有57次妊娠。这些妇女中，60%不是荷兰裔，56%居住在阿姆斯特丹。32名妇女是（曾经的）静脉吸毒者。23名妇女可能是通过异性传播感染；两名妇女还接受过输血。这些妇女中近一半（11/23）来自艾滋病流行地区或其伴侣来自该地区。16名妇女在怀孕前就已知HIV血清阳性。24名妇女因有HIV感染风险因素在孕期或产后1周内接受了专门检测。15名妇女是在阿姆斯特丹（n = 13）和格罗宁根大学医院（n = 2）的孕妇HIV筛查项目中被发现的。起初，其中8名妇女未提及风险因素。35名妇女可选择堕胎（妊娠20周及以内）；大多数（69%）决定继续妊娠。12次妊娠以选择性或自然流产告终，39次妊娠分娩出40名儿童（一对双胞胎），其中39名存活，3名妇女仍在妊娠中，3名妇女的妊娠结局未知。早产（8/39）和出生体重低于2500克（7/39）较为常见，后者尤其在（曾经）使用静脉药物的妇女中（6/25）。
